Bloodstream infections caused by Carbapenemase-producing Enterobacteriaceae (CPE) are often detected after 16 to 72 hours by standard methods, leading to inappropriate treatments and increased mortality.
A new procedure to allow the use of RESIST IVD tests has been developed for detecting CPE directly from positive blood culture bottles. It can be performed in any microbiology laboratory to help clinicians to rapidly, in less than 30 minutes, identify patients with these difficult-to-treat bloodstream infections for better management.
The reagents of the kit are ready to use and are intended for preparation of blood cultures before performing a RESIST test.
The purpose of the kit is to treat the red blood cells from blood cultures in order to release a bacterial extract suitable for the detection of carbapenemases by any kit from the RESIST range. It can be used with all RESIST kits for the analysis of OXA-48, KPC, NDM, VIM and IMP carbapenemases from positive clinical blood cultures (not validated for OXA-163, OXA-23).
Sensitivity = 100%
Specificity = 100%
Coris RESIST-BC Kit advantages:
This quick and easy-to-use reagent kit accelerates the detection time of CP-GNB in patients with bloodstream infections, and thus :