Antibiotic resistance of Gram-negative bacilli, particularly in Enterobacteriaceae, is a worldwide public health concern for both hospital and community-acquired infections. The priority is to limit their spread through the use of new therapeutic agents and/or new strategies.
Rapid detection of colonisation of the digestive tract by carbapenemaseproducing Gram-negative bacilli (C-PGNB) is of utmost importance in order to limit as much as possible the selective pressure of carbapenems in patients with proven intestinal carriage of C-PGNB.Some methods using selective culture media allow the majority of C-PGNB in the microbiota to be cultured.
A new procedure has been developed that allows the use of RESIST tests from rectal specimens. It can be performed in any microbiology laboratory to help clinicians rapidly identify patients carrying C-PGNB for better management.
The reagents of the kit are intended for the rapid culture of Gram-negative bacteria collected with a rectal swab.
The purpose of the kit is to enrich C-PGNB by rapid selective culture from the rectal swab specimens to obtain a bacterial extract directly suitable for carbapenemases detection with tests from the RESIST range of Coris BioConcept Kits.
It can be used with all RESIST rapid test kits for the analysis of OXA-48, KPC,NDM and VIM carbapenemases from rectal swabs (not validated for IMP,OXA-163 and OXA-23).
ReSCape Kit advantages:
Useful for the screening of CP-BGN carriage by asymptomatic patient
Reduced turn-around time (TAT)
Better infection control management in outbreak setting